S$ 270+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19-5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — CUZ
24 Mar — 31 Mar1
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 22 February 2026.

Mon 1-620:05
PTY
-
LIM
Nonstop3h 35m
Copa Airlines
Tue 30-607:00
LIM
-
PTY
Nonstop3h 45m
Copa Airlines
Deal found 20-2S$ 493
Thu 26-302:55
PTY
-
CUZ
1 stop8h 25m
Avianca
Fri 10-417:10
CUZ
-
PTY
1 stop16h 05m
Avianca
Deal found 18-2S$ 520
Mon 1-621:20
PTY
-
LIM
Nonstop3h 35m
Copa Airlines
Mon 31-804:00
LIM
-
PTY
Nonstop3h 37m
Copa Airlines
Deal found 20-2S$ 553
Wed 25-309:45
PTY
-
CUZ
1 stop25h 35m
Avianca
Sun 12-417:10
CUZ
-
PTY
1 stop23h 50m
Avianca
Deal found 18-2S$ 572
Sat 30-519:07
PTY
-
LIM
Nonstop3h 38m
Copa Airlines
Tue 9-613:20
LIM
-
PTY
Nonstop3h 45m
Copa Airlines
Deal found 20-2S$ 574
Sun 15-312:01
PTY
-
LIM
Nonstop3h 39m
Copa Airlines
Wed 25-316:40
LIM
-
PTY
Nonstop3h 43m
Copa Airlines
Deal found 20-2S$ 581
Tue 24-309:45
PTY
-
CUZ
1 stop25h 35m
Avianca
Sun 12-417:10
CUZ
-
PTY
1 stop23h 50m
Avianca
Deal found 18-2S$ 586
Tue 24-314:55
PTY
-
CUZ
1 stop20h 25m
Avianca
Fri 10-417:10
CUZ
-
PTY
1 stop16h 05m
Avianca
Deal found 18-2S$ 599
Fri 6-308:47
PTY
-
LIM
Nonstop3h 38m
Copa Airlines
Thu 12-307:00
LIM
-
PTY
Nonstop3h 41m
Copa Airlines
Deal found 20-2S$ 601
Wed 25-309:45
PTY
-
CUZ
1 stop25h 35m
Avianca
Mon 13-417:10
CUZ
-
PTY
1 stop7h 55m
Avianca
Deal found 18-2S$ 605
Thu 20-812:04
PTY
-
LIM
Nonstop3h 36m
Copa Airlines
Mon 24-802:35
LIM
-
PTY
Nonstop3h 37m
Copa Airlines
Deal found 20-2S$ 614
Tue 24-309:45
PTY
-
CUZ
1 stop25h 35m
Avianca
Mon 13-417:10
CUZ
-
PTY
1 stop21h 05m
Avianca
Deal found 18-2S$ 618

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 22 February 2026. In the last 7 days, Cheapflights users made a total of 200,618 searches

Fly to

Cuzco

Route

Depart

Return

Price

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Fri 27-3

12:01-15:40

Nonstop3h 39m

Lima J Chavez Intl

Sun 12-4

07:00-10:45

Nonstop3h 45m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Wed 15-4

21:18-00:55

Nonstop3h 37m

Lima J Chavez Intl

Sat 18-4

02:35-06:10

Nonstop3h 35m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Mon 9-3

08:47-12:25

Nonstop3h 38m

Lima J Chavez Intl

Sat 21-3

07:00-10:41

Nonstop3h 41m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Sat 25-4

12:03-15:40

Nonstop3h 37m

Lima J Chavez Intl

Sat 2-5

04:00-07:39

Nonstop3h 39m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Tue 7-7

21:44-01:20

Nonstop3h 36m

Lima J Chavez Intl

Sun 12-7

02:15-05:52

Nonstop3h 37m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Fri 3-4

21:43-01:20

Nonstop3h 37m

Lima J Chavez Intl

Tue 7-4

16:40-20:25

Nonstop3h 45m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Thu 23-7

21:19-00:55

Nonstop3h 36m

Lima J Chavez Intl

Wed 29-7

02:35-06:12

Nonstop3h 37m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Fri 13-3

20:00-23:40

Nonstop3h 40m

Lima J Chavez Intl

Sat 21-3

03:30-07:09

Nonstop3h 39m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Tue 21-4

15:38-19:15

Nonstop3h 37m

Lima J Chavez Intl

Sat 25-4

02:35-06:10

Nonstop3h 35m

S$ 493

Panama CityLima

PTY - LIM

PTYLIM

Panama City Tocumen Intl

Fri 20-3

19:04-22:45

Nonstop3h 41m

Lima J Chavez Intl

Sun 22-3

13:20-17:01

Nonstop3h 41m

S$ 493

Flights are sorted by cheapest return flights first.

Deals found on 20-2

Showing 1-10 of 40 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Cuzco. Price data was last updated on 18 February 2026.

The price you pay for your flight from Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 58 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City?

Currently, April is the cheapest month in which you can book a flight from Panama City (average of S$ 400). Flying from Panama City in December will prove the most costly (average of S$ 491). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 22 February 2026.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Bocas del Toro. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest month to fly from Panama City?

    Currently, the cheapest month for flights from Panama City is April. The most expensive month for flights is December. The cheapest prices are shown above but prices will vary according to departure times, airlines, class and how early you book.

  • How does Cheapflights help users find flights from Panama City?

    900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight from Panama City today with Cheapflights!

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

  • Can Cheapflights find flights from Panama City with no change fees?

    Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights offers price alerts on flights from Panama City so you can book your travels when it’s right. The Price Alerts feature is available by clicking the bell icon next to the flight deals above and providing your email address.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight from Panama City today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights simply makes it quick and affordable to book flights from Panama City by bringing together all flight options from hundreds of airlines and agencies online — and we put them in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Panama City with no change fees?

Certainly. Search results for flights from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights offers price alerts on flights from Panama City so you can book your travels when it’s right. The Price Alerts feature is available by clicking the bell icon next to the flight deals above and providing your email address.

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